Before the Mansion. Before the disaster. Evil is Born. Something terrible is seeping into the once pristine mountain air. The residents of Raccoon City go about their lives unaware of the dark fate that surrounds them. It's only the beginning! Sent in to investigate a series of grisly murders in the area, S.T.A.R.S. Bravo Team scrambles into action.

Along the way, Rebecca will encounter Billy Coen, an ex-Marine convicted on circumstantial evidence for the murder of 23 people. When his transport is overturned and infested, his life crosses path with Rebecca. He battles to clear his name and fights to stay alive.

You face your fears to survive and unfold the truth. The door to safety is shut. There is no turning back...

  • New Control Scheme – Classic game that is now playable with your Wii-mote
  • "Partner Zapping" System – Instead of choosing a single character to play through the whole game, the player controls both the main characters, Rebecca Chambers and Billy Coen, simultaneously through the entire game calling on the player to make strategic choices.
  • Realistic Item Management – player can now drop items on the floor to make room for new ones, which they can later retrieve for future use. The locations of dropped items are displayed on the player's map.
  • Traditional Survival Horror – the last of the main titles to use the original Resident Evil gameplay system prior to Resident Evil 4